A review and viewpoint research paper by Sangam L. Dwivedi, Pat Heslop-Harrison, Charles Spillane, Peter C. McKeown, David Edwards, Irwin Goldman and Rodomiro OrtizTrends in Plant Science, on-line first https://doi.org/10.1016/j.tplants.2023.01.006 and 2023 Deleterious mutations are genetic changes that negatively impact the function and fitness of an organism. Our new review paper highlights how some deleterious…
Category: Research
Research in the Molecular Cytogenetics group
Enset in Ethiopia as a poorly characterized but resilient starch staple: review article
349. Borrell JS, Biswas MK, Goodwin M, Blomme G, Schwarzacher T, Heslop-Harrison JS, Wendawek AM, Berhanu A, Kallow S, Janssens S, Molla EL, Davis AP, Woldeyes F, Willis K, Demissew S, Wilkin P. 2019. Enset in Ethiopia: a poorly characterized but resilient starch staple. Annals of Botany 123: mcy214 online first https://doi.org/10.1093/aob/mcy214 (freely available download) Author version: borrell_enset_review_author_version_plusfiguresauthorversionDownload • Background Enset…
ImmunoFISH – Simultaneous visualisation of proteins and DNA sequences gives insight into meiotic processes in nuclei of grasses
Sepsi A, Fábián A, Jäger K, Heslop-Harrison JS, Schwarzacher T. ImmunoFISH: simultaneous visualisation of proteins and DNA sequences gives insight into meiotic processes in nuclei of grasses. Frontiers in Plant Science. 9: 1193. https://doi.org/10.3389/fpls.2018.01193 ImmunoFISH is a method combining immunolabelling (IL) with fluorescent in situ hybridisation (FISH) to simultaneously detect the nuclear distribution of proteins and specific DNA…
An Immortalized Genetic Mapping Population for Perennial Ryegrass: A Resource for Phenotyping and Complex Trait Mapping
Velmurugan J, Milbourne D, Connolly V, Heslop-Harrison JS, Anhalt UC, Lynch MB, Barth S. 2018. An immortalized genetic mapping population for perennial ryegrass: a resource for phenotyping and complex trait mapping. Frontiers in Plant Science 9: article 717. https://doi.org/10.3389/fpls.2018.00717 To address the lack of a truly portable, universal reference mapping population for perennial ryegrass, we have…
New Project on Molecular Cytogenetics and Genomics of Ensete banana
We have a research project starting in 2017 on Ethiopian banana, Ensete ventricosum, for 18 months, in collaboration with Royal Botanic Gardens, Kew (Dr Paul Wilkin) and University of Addis Ababa (Professor Sebsebe Demissew). There is a post-doctoral position working with the project (closed 7 August 2017). The project “Modelling and genomics resources to enhance…
Molecular Cytogenetics Group – an infographic of what we do
Infographic: what we do in the Molecular Cytogenetics Research Group
Saffron crocus, cooking and Iran on the radio
The spice Saffron is valued worldwide for its flavor, aroma and color. I’ve just broadcast an interview with Robin Young produced by Jill Ryan for NPR’s Here and Now program which let me tell you something about my enjoyment of saffron both as a consumer and scientist. Saffron is unusual in that it is equally…
Diversity and characters in Ethiopian linseed Linum #PAGXXIII Negash Worku
Many people have talked about Orphan crops – those where there has been little genetic or other research – and the characterization, evaluation and exploitation of germplasm at the #PAGXXIII Plant and Animal Genome Conference this week. Today, I am talking about work by Negash Worku on the Diversity and Characters in Ethiopian Linseed Accessions….
Transposable Elements in the Musa and Banana Genome: PAGXXIII conference talk
There has been a lot of talk about transposable elements during the Plant and Animal Genome #PAGXXIII meeting this week. As half or more – often 75% – of all the DNA in a plant or animal genome is typically made of class I retrotransposons and class II DNA transposons, this widespread interest is right!…
Needs for understanding water and food security
“The earth’s land surface receives about 110,000 km3 of rainfall annually. More than half of this water is evapotranspired (transmitted from soils and through plants to the air); about 20,000 km3 falls on land that is cultivated in some form; and about 40,000 km3 becomes available in dams, lakes, rivers, streams and aquifers for human…
Evidence of convergent evolution in humans and macaques supports an adaptive role for copy number variation of the β-defensin-2 gene
Ottolini B, Hornsby MJ, Abujaber R, Macarthur JA, Badge RM, Schwarzacher T, Albertson DG, Bevins CL, Solnick JV, Hollox EJ. 2014. Evidence of convergent evolution in humans and macaques supports an adaptive role for copy number variation of the β-defensin-2 gene. Genome Biology and Evolution 6(11): 3025-3038. DOI: 10.1093/gbe/evu236 β-defensins are a family of important peptides of…
Molecular cytogenetics research group October 2014
At our lab. meeting a couple of weeks ago, we were happy to welcome two new PhD students to the group. Here we all are in the lobby of our Adrian Building. We are from six countries, and work on a diverse range of molecular cytogenetics projects. From left to right, left of DNA molecule:…
Chromosomal evolution in Brachiaria forage grasses with Fabiola Carvalho Santos
Fabiola Santos from University of Londrina, Brazil, is working on the Chromosomal evolution and the organization of repetitive DNA sequences in diploid and polyploid Brachiaria forage grasses in the molecular cytogenetics group in Leicester. Brachiaria is most important cultivated forage grass genus in Brazil (with billion-dollar production), and the genus includes diploid and polyploid species with similar…
An Overview of Peanut Genome Structure
308. DJ Bertioli, ACG Araujo, S Nielen, P Heslop-Harrison, PM Guimarães, T Schwarzacher, S Isobe, K Shirasawa, Leal-Bertioli SCM. 2014. An overview of peanut genome structure. Chapter 6 in Genetics, Genomics and Breeding of Peanuts. Eds Nalini Mallikarjuna, Rajeev K. Varshney. Peanut genome structure manuscript Author Version pp. 114-138. CRC Press, Florida. http://www.crcnetbase.com/doi/abs/10.1201/b16872-7 ABSTRACT Cultivated peanut (Arachis hypogaea…
Sugar cane and characterization of Saccharum hybrids by molecular cytogenetics with Natalia Melloni
Natália Melloni from UNESP and IAC, Brazil, has been characterizing Saccharum sugar cane hybrids in a collaboration with the molecular cytogenetics group. The title of the project is “Characterization of interspecific hybrids (Saccharum spp x Saccharum spontaneum) by molecular cytogenetics” or “Caracterização de híbridos interespecíficos (Saccharum spp x Saccharum spontaneum ) por citogenética molecular”, and…
Molecular cytogenetics, genome evolution and agricultural genomics 