Obituary for Dr Mark Goodwin

I am so saddened to write about the sudden death of my good friend, colleague and co-project leader, Mark Goodwin. We had very extensive common interests in the application and delivery of research for developing countries, research ethics, and in the role and importance of tertiary education and pedagogy. His inputs to my thinking about…

Innovative science and blue-sky research

321. Braben DW, Heslop-Harrison JS and 48 others. 2015. Letter: Innovative science, Blue Sky research, scientific enterprise and prosperity. The Times (London) 23 September 2015. p. 28.  (http://www.thetimes.co.uk/tto/opinion/letters/article4564669.ece ££) The Times (London) September 23, 2015 Wednesday Edition 1; Letter on Innovative scienceSECTION: EDITORIAL; OPINION; LEADING ARTICLES; Pg. 28 Sir, “Blue sky” research is vital to scientific enterprise…

In situ hybridization: a course on FISH and ChIp

In situ hybridization – a course on FISH and ChIp In situ hybridization, now largely with fluorescent detection so ‘fluorescent in situ hybridization’ or FISH, is a key method for localizing DNA sequences along chromosomes and occassionally within interphase nuclei. RNA in situ hybridization (not discussed here) is used for locating gene transcripts within nuclei….

Plant nuclear genome composition

299. Heslop-Harrison, JS (Pat); and Schmidt, T (August 2012) Plant Nuclear Genome Composition. In: eLS 2012, John Wiley & Sons Ltd: Chichester http://www.els.net/ Author-prepared preprint linked here. Subscription DOI:  http://onlinelibrary.wiley.com/doi/10.1002/9780470015902.a0002014.pub2/abstract (but this link seems not to work: http://dx.doi.org/10.1002/9780470015902.a0002014.pub2 Nov 2012). Intranet: http://www.le.ac.uk/biology/phh4/HHpubs/ELS_PlantGenomes_SchmidtHH.pdf due Nov 2012). The plant nuclear genome consists of DNA divided among the chromosomes within the cell nucleus. Plant…